Ffar1 CLIA Kit for Mouse(Mus musculus) | EIAab.comFfar1 CLIA Kit for Mouse(Mus musculus)

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Ffar1 (Gene name),

Free fatty acid receptor 1 (Protein name ), FFAR1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ffar1(Gpr40);

Protein name:

Free fatty acid receptor 1;

Alternative:

G-protein coupled receptor 40;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

Receptor for medium and long chain saturated and unsaturated fatty acids. Binding of the ligand increase intracellular calcium concentration and amplify glucose-stimulated insulin secretion. The activity of this receptor is mediated by G-proteins that activate phospholipase C. Seems to act through a G(q) and G(i)-mediated pathway.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

300

Sequence:

50:

100:

150:

200:

250:

300:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q76JU9

STRING:

10090.ENSMUSP00000055564

Pfam:

PF00001

SMR:

Q76JU9

UniGene:

Mm.425422

KEGG:

mmu:233081

Uniprot:

Q76JU9

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ELISA Kit for Mouse Free fatty acid receptor 1

Cat.:

E9934h

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96T

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ELISA Kit for Mouse Free fatty acid receptor 1

Cat.:

E9934m

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96T

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ELISA Kit for Mouse Free fatty acid receptor 1

Cat.:

E9934r

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96T

CLIA Kit for Mouse Free fatty acid receptor 1

Cat.:

U9934m

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96T

CLIA Kit for Mouse Free fatty acid receptor 1

Cat.:

U9934r

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96T

CLIA Kit for Mouse Free fatty acid receptor 1

Cat.:

U9934h

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96T

Polyclonal Antibody for Mouse Free fatty acid receptor 1

Cat.:

P9934Rb-r

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40ug/0.2ml

Polyclonal Antibody for Mouse Free fatty acid receptor 1

Cat.:

P9934Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse Free fatty acid receptor 1

Cat.:

P9934Rb-m

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40ug/0.2ml

Monoclonal Antibody for Mouse Free fatty acid receptor 1

Protein for Mouse Free fatty acid receptor 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"The orphan G protein-coupled receptor GPR40 is activated by medium and long-chain fatty acids."
Briscoe C.P. , Tadayyon M. , Andrews J.L. , Benson W.G. , Chambers J.K. , Eilert M.M. , Ellis C. , Elshourbagy N.A. , Goetz A.S. , Minnick D.T. , Murdock P.R. , Sauls H.R. Jr. , Shabon U. , Spinage L.D. , Strum J.C. , Szekeres P.G. , Tan K.B. , Way J.M. , more...
J. Biol. Chem.278:11303-11311(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];TISSUE SPECIFICITY
strain: BALB/c.
2.

"Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40."
Itoh Y. , Kawamata Y. , Harada M. , Kobayashi M. , Fujii R. , Fukusumi S. , Ogi K. , Hosoya M. , Tanaka Y. , Uejima H. , Tanaka H. , Maruyama M. , Satoh R. , Okubo S. , Kizawa H. , Komatsu H. , Matsumura F. , Noguchi Y. , more...
Nature422:173-176(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
4.

"Free fatty acid receptor 1 (FFA(1)R/GPR40) and its involvement in fatty-acid-stimulated insulin secretion."
Salehi A. , Flodgren E. , Nilsson N.E. , Jimenez-Feltstrom J. , Miyazaki J. , Owman C. , Olde B.
Cell Tissue Res.322:207-215(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
5.

"GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo."
Latour M.G. , Alquier T. , Oseid E. , Tremblay C. , Jetton T.L. , Luo J. , Lin D.C. , Poitout V.
Diabetes56:1087-1094(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
6.

"The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding."
Kebede M. , Alquier T. , Latour M.G. , Semache M. , Tremblay C. , Poitout V.
Diabetes57:2432-2437(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
7.

"The free fatty acid receptor G protein-coupled receptor 40 (GPR40) protects from bone loss through inhibition of osteoclast differentiation."
Wauquier F. , Philippe C. , Leotoing L. , Mercier S. , Davicco M.J. , Lebecque P. , Guicheux J. , Pilet P. , Miot-Noirault E. , Poitout V. , Alquier T. , Coxam V. , Wittrant Y.
J. Biol. Chem.288:6542-6551(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
8.

"Activation of FFA1 mediates GLP-1 secretion in mice. Evidence for allosterism at FFA1."
Xiong Y. , Swaminath G. , Cao Q. , Yang L. , Guo Q. , Salomonis H. , Lu J. , Houze J.B. , Dransfield P.J. , Wang Y. , Liu J.J. , Wong S. , Schwandner R. , Steger F. , Baribault H. , Liu L. , Coberly S. , Miao L. , more...
Mol. Cell. Endocrinol.369:119-129(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;ENZYME REGULATION;DISRUPTION PHENOTYPE
9.

"A novel antidiabetic drug, fasiglifam/TAK-875, acts as an ago-allosteric modulator of FFAR1."
Yabuki C. , Komatsu H. , Tsujihata Y. , Maeda R. , Ito R. , Matsuda-Nagasumi K. , Sakuma K. , Miyawaki K. , Kikuchi N. , Takeuchi K. , Habata Y. , Mori M.
PLoS ONE8:E76280-E76280(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;ENZYME REGULATION

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